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WashU Innovation: Stent that Prevents Endoleaks for Fusiform Aneurysms

WashU Innovation: Stent that Prevents Endoleaks for Fusiform Aneurysms A stent for popliteal fusiform aneurysms that prevents endoleaks has been developed. SPARTA is able to functionalize existing stents and initiates blood clotting within the aneurysm sac, creating a solid biological barrier that blocks all types of endoleaks. Fibrosis over the blood clot is also induced which results in a reduction in the size of the aneurysm.

SPARTA consists of a nitinol frame (gold in figure below) supporting a lattice of silk sutures (blue). The silk sutures contain thrombogenic material that triggers the blood coagulation cascade. The nitinol frame is compressed into the sheath for deployment and once inside, expands to provide equal distribution of silk suture within the aneurysm sac. SPARTA has been designed for popliteal aneurysms but could be applied to other (non-brain) aneurysms as well.

For more information, email otm@wustl.edu.

Aneurysms

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