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Resistant to Base!

Resistant to Base! An organic chemistry-themed music video parodying Robert Palmer's 1985 "Addicted to Love."



Shot on Canon XL-1s (MiniDV) w/ Canon XL 5.5-88mm IS II 16X lens. Edited on Sony Vegas HD 6.



***LYRICS***

Your lights are on, but you're not home

You're in the lab, working alone.

Your synthesis is nearly done

Just add a chain to that carbon.



You can't wait to alkylate

But first you must deprotonate

You add a mole of LDA

To overcome that pKa



Whoa, you like to think it will react with the stuff, oh yeah

It's closer to the truth to say you can't add enough

You know you're gonna have to face it, it's resistant to base.



You check pH, it's past fourteen

Your stirring bar is dissolving

The TLC shows no products

Another mole and then reflux!



With LDA, it won't react

Butyllithium just might abstract

That hydrogen that won't obey

Le Chatelier's communiqué



Whoa, you like to think it will react with the stuff, oh yeah

It's closer to the truth to say you can't add enough

You know you're gonna have to face it, it's resistant to base.



REFRAIN

Might as well face it, it's resistant to base. (x5)



Your potassium t-butoxide

And ammonium hydroxide

Your KOH and hydrazine

Push the pH beyond eighteen



REFRAIN

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